Posts

Long COVID symptoms don't resolve due to subsequent vaccinations

Image
A new study from Mount Sinai  followed 453 COVID-19 patients with  post-acute sequelae of COVID ( PASC). 324 (72%) of them were vaccinated in the following 6 months. Unadjusted analyses did not show significant changes in anosmia, respiratory symptoms, depression, anxiety, PTSD, or quality of life ( p  > 0.05 for all comparisons) among vaccinated vs. unvaccinated patients. Similar results were found in propensity-adjusted comparisons and in secondary analyses based on the number of vaccine doses received. An older not-yet-peer-reviewed study  found that those who were vaccinated before catching COVID had only a 13% lower risk than unvaccinated patients of having PASC symptoms (mostly lung-related) six months later .  According to the lead author of this study, reliance on vaccination as a sole mitigation strategy is wholly inadequate. Here are a few case reports about Long COVID in the vaccinated individuals.   CASE REPORTS A previously healthy 47-year-old woman was evaluated for

Fatal Breakthrough COVID-19 in a Heart Transplant Recipient

Image
A 71-year-old male presented with two days’ shortness of breath, myalgias, and chills in March 2021.  His temperature was 99.0 °F and heart rate was 108 beats/minute. The patient had received two doses of the COVID-19 vaccine four weeks apart, with the second dose 16 days prior to admission. Laboratory exams were significant for lymphopenia and acute kidney injury (AKI).  His brain natriuretic peptide (BNP) level was found to be elevated (an indicator of heart failure). A chest X-ray showed cardiomegaly with pulmonary vascular engorgement and an electrocardiogram showed an atrial-sensed, ventricular-paced rhythm. 5 years prior the patient received an orthotopic heart transplant. The biopsy ruled out rejection. He also had a history of obesity, hypertension, unprovoked deep vein thrombosis, and dual chamber pacemaker. The patient was started on dexamethasone and remdesevir and his tacrolimus dose was adjusted to maintain therapeutic serum levels. The patient’s AKI improved with fluid re

Fatal autoimmune acquired factor XIII/13 deficiency after COVID‐19 vaccination

Image
A 78‐year‐old woman with no personal or family history of abnormal bleeding noticed a bruise on her thigh 2 weeks after her second COVID‐19 mRNA vaccination (Pfizer‐BioNTech). Her skin bruise persisted and on day 38, a new bruise appeared on her left hand. On day 50, she visited a hospital because of pain and swelling in the left hand.  Computed tomography (CT) scans showed intra‐articular bleeding in her left shoulder and asymptomatic central nervous system (CNS) bleeding. Blood tests revealed normocytic anemia. While factor XIII/13 (F13) antigen level was slightly reduced, and its activity was below the detection limit. The patient died of CNS bleeding despite treatment.  READ MORE REFERENCE Shimoyama S, Kanisawa Y, Ono K, Souri M, Ichinose A. First and fatal case of autoimmune acquired factor XIII/13 deficiency after COVID‐19/SARS‐CoV‐2 vaccination. American journal of hematology. 2022 Feb;97(2):243.

Triple-vaccinated 70-year-old dies from breakthrough COVID-19 during the Omicron wave

Image
Previously healthy and fit (bicycling, scuba diving) 70-year-old man became ill with COVID-19 in December 2021. He was fully vaccinated and boosted. When his breathing became labored, he was admitted to the emergency room at George Washington University Hospital. His treatment included a monoclonal antibody.  But despite his robust good health and fitness level, he never left the hospital. He died after spending a month in the hospital. One of his last acts of generosity occurred as he was dying. Some of his blood was drawn for COVID-19 research that will hopefully save lives.  REFERENCES https://www.washingtonpost.com/health/2022/04/29/covid-deaths-unvaccinated-boosters/ https://dc.eater.com/2022/1/18/22881891/scott-bennett-amsterdam-falafelshop-adams-morgan-death https://www.nbcwashington.com/news/coronavirus/founder-of-amsterdam-falafel-shop-dies-of-covid-after-month-in-hospital/2937497/ https://www.gofundme.com/f/to-be-continued-the-scott-bennett-memorial-fund

Fatal Guillain-Barré syndrome after AstraZeneca COVID-19-vaccination

Image
A  fit and healthy 77-year-old woman  got her first dose of the AstraZeneca vaccine in July 2021. Within weeks she went from doing her own shopping and loading firewood to being paralyzed, relying on her children and hospital staff to hand-feed her. She also experienced delusions and hallucinations.  She died in hospital on September 5 last year, leaving four children, six grandchildren and three cats. The cause of death listed on her death certificate is "Guillain-Barre syndrome in the setting of recent AstraZeneca vaccination". The  Therapeutic Goods Administration  (TGA) of Australia has identified 11 deaths linked to the first dose of AstraZeneca – "eight were thrombosis with thrombocytopenia syndrome (TTS) cases, two were linked to Guillain-Barre syndrome (GBS), and one was a case of immune thrombocytopenia (ITP)". REFERENCES https://www.abc.net.au/news/2022-05-17/covid-vaccines-booster-astrazeneca-australian-deaths/101055494 https://www.msn.com/en-au/health/me

Increased cardiovascular emergencies during vaccine rollout

Image
Using a unique dataset from Israel National Emergency Medical Services (EMS) from 2019 to 2021, a n increase of over 25% was detected in both  cardiac arrest (CA) and acute coronary syndrome (ACS) EMS calls  during January–May 2021, compared with the years 2019–2020.  This study leveraged the Israel National EMS (IEMS) data system and analyzed all calls related to CA and ACS events over two and a half years, from January 1st, 2019, throughout June 20th, 2021. U sing Negative Binomial regression models, the weekly emergency call counts were significantly associated with the rates of 1st and 2nd vaccine doses administered to this age group but were not with COVID-19 infection rates.  These findings are emphasized by Figures  that present the graphs described in the “ Methods ” section for both CA and ACS, CA only, and ACS only, respectively. Both the CA and ACS call counts (red curve) start increasing early January 2021 and seem to track closely the 2nd dose curve (solid blue curve). Th

15-year-old boy commits suicide after cyberbullying for false rumor of being non-vaccinated

Image
It’s heartbreaking what is happening in society right now . A 15-year-old boy enrolled at a prestigious private school had a promising future — that is, until his parents say he became a victim of relentless cyberbullying by his classmates. He initially targeted by a false rumor that he was unvaccinated was bullied relentlessly until he took his own life in January . The lawuit filed on April 25, 2022 against the  Latin School of Chicago  alleges administrators at the private college prep school committed “willful failure” to stop the incessant bullying,  the Chicago Tribune reported . The Cook County filing named the school, several employees and parents of the alleged bullies as defendants. The late teen transferred to the school due to its in-person learning during the coronavirus pandemic, the complaint states. A student whose parents are named in the lawsuit then started spreading a rumor that the 10th-grader, Nate Bronstein, was unvaccinated, according to the lawsuit. Nate actua