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Prolonged Diarrhea after COVID-19 vaccination

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A 46-year-old woman with no notable medical history developed repeated vomiting approximately four hours after receiving the first BNT162b2 mRNA COVID-19 vaccine. Seven days after the first vaccination, she further developed 3–5 loose-to-liquid stools per day, which corresponded to type 6 on the Bristol Stool Form (BSF).  Two weeks after the first vaccine dose, intermittent paraumbilical pain developed with associated loss of appetite. The patient decided to receive the second dose 21 days after the first dose, which furthered worsened her condition.  Vomiting and diarrhea progressed, with 7–10 watery stools per day (BSF type 7). Blood tests performed 4 weeks after the second dose revealed normal levels of total and differential white blood cell (WBC) counts and serum C-reactive protein (CRP), slightly elevated D-dimer serum level (1.1 μg/mL), and slightly elevated serum C1 esterase inactivator activity. SARS-CoV-2 rapid antigen test was negative. Eight weeks after...