Canadian man diagnosed with Guillain-Barré Syndrome following 1st dose of ChAdOx1-S vaccine unable to get an exemption from 2nd dose

A ~30-40-year-old male was given a dose of the AstraZeneca vaccine in April 2021. Within days, he started to have excruciating back pain. Then came the tingles on the side of his face — and then, paralysis.

He was diagnosed with Guillain-Barré Syndrome (GBS), a rare condition that affects the nervous system. It can cause paralysis, muscle weakness, and even death. 

This condition has been linked to COVID-19 vaccination with all types of vaccines and wide range of ages (eg, Pfizer: 67-year-old male, Pfizer: 14-year old male,  Astrazeneca: 66-year old male)

Review of 9 cases that occurred in persons with a mean age of 57.8 (range 20–86) years,  56.4% male, showed that most of the reported case-patients received ChAdOx1-S (25/39), followed by BNT162b2 (12/39) (Pfizer-BioNTech), Ad26.COV2.S (1/39) (Johnson & Johnson), and CoronaVac (1/39). The GBS rate after COVID-19 vaccination ranged from 1.8 to 53.2 cases/1 million doses. There were two deaths associated with Ad26.COV2.S-induced GBS in South Africa. 

The Canadian man spent two months in the hospital, and the condition has left him unable to work as he tries to access slow-moving government support for vaccine injury.

He's been unable to get an exemption from receiving the 2nd dose of COVID-19 vaccine, with health officers saying they can't prove his GBS was caused by the AstraZeneca shot — and advising him to get a second dose of a different COVID-19 vaccine. 


REFERENCE

B.C. man who had rare, extreme reaction to COVID-19 vaccine still waiting for exemption, government support | CBC News

Comments

Post a Comment

Popular posts from this blog

A New Onset of Ulcerative Colitis post-2nd-breakthrough-COVID-19

Image
A 21-year-old non-smoking Caucasian male with a history of acute pancreatitis but no other medical issues or family history had two doses of the BNT162b2 mRNA COVID-19 vaccine.  Four months after the second dose he had his first episode of COVID-19. Although not hypoxic, he felt pretty unwell for a week, with a severe cough, fever, generalized body ache, headache, and loss of taste. He received the third dose of the vaccine two months after recovering from COVID. Nine months after the third dose, he had the second episode of COVID-19, during which he was mildly unwell for three days, recovered, and did not require any anti-viral medication or antibiotics. One week post the second episode of COVID-19, he developed diarrhea and abdominal pain. It then progressed to bloody diarrhea. Ulcerative colitis was diagnosed based on his clinical symptoms, biopsy changes, and the exclusion of other causes.  There are ten published case reports about the newly diagnosed ulcerative colitis associate
Read more

Navigating the Tripledemic: JN.1, RSV, and Flu Update

Image
The respiratory viruses are out there.  Wastewater viral activity levels for COVID-19 , as reported by the Centers for Disease Control and Prevention, have reached the highest point since the Omicron surge in 2022. The levels are also high in Canada . The three primary respiratory illnesses continue to circulate at very high levels. But despite the triple threat of  SARS-Cov-2, respiratory syncytial virus ( RSV ) and the flu , there is a notable lack of community attention.   JN.1 (Pirola,  BA.2.86 ,  with additional L455S mutation, descending from a  de-escalated  variant of concern BA.2), initially detected on August 25 2023, has evolved from a variant under monitoring to a  variant of interest. Variants like Acrux (XBB.2.3, that began to spread worldwide soon after WHO declared the end of the pandemic) are  no longer relevant , but a few now less prevalent variants such as  Centaurus  (BA.2.75) and XBB, a hybrid of Centaurus with BA.2 lineage, that  gave rise to  Eris , its descend
Read more

Chronic SARS-CoV-2 Shedding

Image
Chronic viral shedding, a condition where the virus continues to be released from an individual's body long after the initial infection, has been observed in many infectious diseases, including COVID-19.  In such cases, individuals may remain asymptomatic or experience only mild symptoms while the virus persists. It remains detectable in repeated tests over an extended period and can still infect others even in nasal swab is negative. This was evident in our study.    Recent research by Conway et al. (2024) highlights the possibility of chronic SARS-CoV-2 infection, extending over several months and potentially years. Other studies have documented prolonged asymptomatic infections and extended viral shedding in moderate to severe beyond hospital discharge. Analysis of sequencing data on UK samples taken between 2 November 2020 and 15 August 2022 lead to estimates that 0.1–0.5% of infections may become persistent with typically rebounding high viral loads and last for at least 60 da
Read more