Fatal Breakthrough cases in the BA.5/BA.4.6/BF.7 era
Decreased Case Fatality Rate (CRD) in the Omicron era was largely a result of the decreased pathogenicity of Omicron. In one study of 101 470 patients, mortality rates were 0.7% for Delta (B.1.617.2), 0.4% for Omicron (B.1.1.529), and 0.3% for Omicron (BA.2) subvariants. Yet, people keep dying from COVID even in the BA.5/BA4.6 variants era, since the severity of symptoms is affected by age and other health conditions.
One of the most recent October 2022 COVID-19 fatalities was a 62-year-old veteran competitive bodybuilder. He completed his primary vaccination series in April 2021. A 67-year old theoretical physicist died on October 19th from complications of COVID-19 he had in September. A 63-year-old person with Navajo ancestry died after her 10-month battle with the original strain of Omicron.By May 2022, more vaccinated individuals aged 90 or more died from COVID-19 than unvaccinated elderly of the same age. By mid-October 2022, cumulative incidence of breakthrough deaths started to exceed non-vaccinated deaths among all ages (see stats for Canada for Sep. 2022).
In August of 2021, about 18.9% of COVID-19 deaths occurred among the vaccinated. Six months later, in February 2022, that proportional percent of deaths had increased to more than 40%.
Comparatively, in September 2021, just 1.1% of COVID-19 deaths occurred among Americans who had been fully vaccinated and boosted with their first dose. By February 2022, that percentage had increased to about 25%.
Fitness Volt, "Bodybuilding Icon Doug Brignole Passes Away At 63," Oct. 14, 2022
YouTube, "Doug Bringnole Path to Mr. Universe V5"