Complex Regional Pain Syndrome after Vaccination
A 17-year-old woman with no specific medical history received the first dose of Pfizer/BioNTech mRNA COVID-19 vaccine on her left upper arm, which caused mild swelling at the site of injection and resolved quickly. Three weeks later, the second dose of the vaccine was administered to her left upper arm, and after a fever which resolved within a few hours, a bruise appeared on the back of her left hand that spread to her entire left hand, became edematous and caused severe pain.
Horisawa S, Ando T, Kawamata T, Taira T. Complex regional pain syndrome after mRNA-based COVID-19 vaccination. Clin Neurol Neurosurg. 2022 Dec 28;224:107578. doi: 10.1016/j.clineuro.2022.107578. Epub ahead of print. PMID: 36584585; PMCID: PMC9796353.
Raman P. Complex Regional Pain Syndrome Post COVID-19 Vaccine Shot: An Autobiographical Case Report. Cureus. 2021 Dec 8;13(12).